APSF News & Updates
Association Between Dexmedetomidine Use and Duration of Invasive Mechanical Ventilation After Cardiac Surgery: A Hospital Registry Study
April 27, 2026
Dexmedetomidine is an alpha-2 adrenergic receptor agonist that may have utility as a sedating infusion to achieve fast-track recovery after cardiac surgery. However, due to the time it takes to…
Incidence of Pain during Cesarean Delivery with Neuraxial Anesthesia: An International, Prospective Cohort Study
April 20, 2026
Pain during cesarean delivery can result in long-term psychological sequelae, including depression and post-traumatic stress disorder, but the incidence of pain during cesarean delivery due to inadequate neuraxial anesthesia is…
EEG-Guided Titration of Sevoflurane and Pediatric Anesthesia Emergence Delirium: A Randomized Clinical Trial
April 13, 2026
Pediatric anesthesia emergence delirium (PAED) is a common complication following surgical procedures in pediatric patients. While general anesthesia appears to be a risk factor for PAED, the etiology of PAED…
Identifying septic shock subgroups to tailor fluid strategies through multi-omics integration
April 6, 2026
Patients have variable responses to different resuscitation strategies for septic shock. For example, while aggressive fluid administration is a mainstay of treatment for septic shock, in some patients this may…
Comparison of Propofol and Dexmedetomidine Infused Overnight to Treat Hyperactive and Mixed ICU Delirium: A Prospective Randomised Controlled Clinical Trial
March 30, 2026
Delirium occurs in about 31% of ICU adults and is associated with longer hospital stays, more complications, increased mortality, higher costs, and worse long-term cognition and independence. Current medical options…
The influence of thirty-degree leg elevation on noradrenaline requirements administered as a prophylactic variable infusion during cesarean delivery, an open-label randomized controlled trial
March 23, 2026
Cesarean delivery is frequently performed under spinal anesthesia. However, despite the administration of prophylactic vasopressors, spinal anesthesia can still result in hypotension with potential maternal and neonatal consequences, including compromised…