APSF News & Updates
Identifying septic shock subgroups to tailor fluid strategies through multi-omics integration
April 6, 2026
Patients have variable responses to different resuscitation strategies for septic shock. For example, while aggressive fluid administration is a mainstay of treatment for septic shock, in some patients this may…
Comparison of Propofol and Dexmedetomidine Infused Overnight to Treat Hyperactive and Mixed ICU Delirium: A Prospective Randomised Controlled Clinical Trial
March 30, 2026
Delirium occurs in about 31% of ICU adults and is associated with longer hospital stays, more complications, increased mortality, higher costs, and worse long-term cognition and independence. Current medical options…
The influence of thirty-degree leg elevation on noradrenaline requirements administered as a prophylactic variable infusion during cesarean delivery, an open-label randomized controlled trial
March 23, 2026
Cesarean delivery is frequently performed under spinal anesthesia. However, despite the administration of prophylactic vasopressors, spinal anesthesia can still result in hypotension with potential maternal and neonatal consequences, including compromised…
Perioperative Practices for Patients of Venezuelan Ancestry
March 13, 2026
In July 2025, the American Society of Anesthesiologists (ASA) along with the Society for Pediatric Anesthesia (SPA) and Wake Up Safe (WUS) issued a joint warning regarding an ongoing safety concern that…
Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis
February 23, 2026
Acetaminophen (paracetamol) is the most-commonly used analgesic in pregnancy, is widely held to be safe in pregnancy, particularly when compared with other analgesics including NSAIDs and opioids. Recent, this safety…
APSF Newsletter – February 2026
February 1, 2026
The Anesthesia Patient Safety Foundation is pleased to announce the release of the February 2026 APSF Newsletter.