October 2015 APSF Newsletter, The Official Journal of the Anesthesia Patient Safety Foundation


New Developments for the Management of Sepsis

Perioperative Fluid Management: Cheers to the Dream of Moderation

Low Tidal Volume Ventilation in the Operating Room—Where Are We Now?

APSF Awards Two Safety Scientist Career Development Awards

HAIs: When in Doubt, Blame Anesthesia. Could They Be Right?

A Japanese Perspective on Patient Safety

Developing Patient Safety Leaders: Leadership Fellows Share Insights

Ultrasound-Guided Subclavian Vein Catheterization: Evidence and Practice

From APSF Educational Videos to Your Practice: How to Make it Happen

Q&A: Reader Questions Fire Risk of Petroleum-Based Products

Dear SIRS: Why Do The Gauss Lines Matter?

Dear SIRS: Safety Issues With Gas Scavenging System in GE Avance and
GE Aespire Anesthesia Machines


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APSF Resident Quality Improvement (RQI) Recognition Award


Letters to the Editor:

Use of Capnography during Moderate Sedation by Non-Anesthesia
Personnel in Various Clinical Settings

Eliminating Ratio Expressions on Single Entity Drug Products

Expert Clarifies Complexity of Unintended ICD Firing


Archives of Past Issues
Sponsorship Opportunities
Corporate Donors
2016 Board and Committees
APSF Newsletter Guide for Authors

—Featured Article—

New Developments for the Management of Sepsis

An experienced health care provider can identify the septic patient with barely a glance, but were you to ask them to define sepsis, many providers would struggle to provide a clear definition. This difficulty likely stems from a failure of understanding of the underlying pathophysiology of sepsis. A new consensus definition, released in early 2016, sought to more clearly define sepsis and septic shock.1 According to these new definitions, sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection, while septic shock is a subset of sepsis in which profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone. [more]

Perioperative Fluid Management: Cheers to the Dream of Moderation


Dr. Stoelting moderates

Fluid management is a fundamental component of the care we give our patients undergoing surgery. Establishing intravenous access and setting up a bag of fluid to flow into a vein is so much a part of everyday working life that we rarely give it much thought. We each have our own personal rationale for our chosen pattern of fluid administration and we probably think that we have pretty standard, mainstream patterns of behavior in our care and deliver a good outcome for our patients. Yet a high degree of variability in both the type and amount of fluid that our patients receive during major surgery is repeatedly reported in the literature, and at the extremes is associated with poor outcome.1-3 [more]



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The Official Journal of the Anesthesia Patient Safety Foundation

The Anesthesia Patient Safety Foundation Newsletter is the official publication of the nonprofit Anesthesia Patient Safety Foundation and is published three times per year in Wilmington, Delaware. Individual subscription–$100, Corporate–$500. Contributions to the Foundation are tax deductible. ©Copyright, Anesthesia Patient Safety Foundation, 2016.

The opinions expressed in this Newsletter are not necessarily those of the Anesthesia Patient Safety Foundation. The APSF neither writes nor promulgates standards, and the opinions expressed herein should not be construed to constitute practice standards or practice parameters. Validity of opinions presented, drug dosages, accuracy, and completeness of content are not guaranteed by the APSF..

APSF Executive Committee:
Robert K. Stoelting, MD, President; Jeffrey B. Cooper, PhD, Executive Vice President; George A. Schapiro, Executive Vice President; Robert J. White, Vice President; Matthew B. Weinger, MD, Secretary; Casey D. Blitt, MD, Treasurer; Robert A. Caplan, MD; David M. Gaba, MD; Steven K. Howard, MD; Lorri A. Lee, MD; Robert C. Morell, MD; A. William Paulsen, PhD; Richard C. Prielipp, MD; Steven R. Sanford, JD; Maria A. van Pelt, PhD, CRNA; Mark A. Warner, MD. Consultants to the Executive Committee: John H. Eichhorn, MD; Bruce P. Hallbert, PhD.

Newsletter Editorial Board:

Robert C. Morell, MD, Co-Editor; Lorri A. Lee, MD, Co-Editor; Steven B. Greenberg, MD, Assistant Editor; Sorin J. Brull, MD; Joan Christie, MD; Jan Ehrenwerth, MD; John H. Eichhorn, MD; Glenn S. Murphy, MD; Wilson Somerville, PhD; Jeffery Vender, MD.

Address all general, contributor, and subscription correspondence to:

Administrator, Deanna Walker
Anesthesia Patient Safety Foundation
Building One, Suite Two
8007 South Meridian Street
Indianapolis, IN 46217-2922
e-mail address: walker@apsf.org

Address Newsletter editorial comments, questions, letters, and suggestions to:

Robert C. Morell, MD
Senior Co-Editor, APSF Newsletter

c/o Addie Larimore, Editorial Assistant
Department of Anesthesiology
Wake Forest University School of Medicine
9th Floor CSB
Medical Center Boulevard
Winston-Salem, NC 27157-1009
e-mail: apsfeditor@yahoo.com

Send contributions to:
Anesthesia Patient Safety Foundation
1061 American Lane
Schaumburg, IL 60167-4973
Or please donate online at www.apsf.org.